Deciphering Transcriptional Regulation in C4 Photosynthesis by Integrating High-Throughput Sequencing and Single-Cell Multiomics Techniques
JOIN USThe Tu lab studies grasses to decipher transcriptional regulation underlying C4 photosynthesis. Combining current high-throughput sequencing (e.g. ChIP-seq, ChIP-exo, ATAC-seq, Hi-C, ChIA-PET and RNA-seq) and single-cell multiomics techniques, the Tu lab explores how the genome non-coding regions determine cell fate and achieve precision temporal and spatial regulation of gene expression.
By understanding how the transcriptional regulatory network fine-tune gene expression, we aim to untangle the complexity of the regulatory processes that underline the evolution and differentiation of photosynthetic systems.
Chromatin openness and three-dimensional structure, histone post-translational modifications, DNA methylation, etc.
Regulatory network construction of transcription factors, co-binding, binding footprints, etc.
The Tu lab investigates the molecular drivers of high photosynthetic efficiency in crops. By integrating multiple photosynthetic measurements (e.g., chlorophyll fluorescence imaging and gas exchange analysis) with multi-omics profiling, we dissect how light-energy capture, electron transport, and carbon assimilation are synergistically optimized.
We welcome undergraduate Tianming Huang to join Tu Lab for for his graduation project.
Congratulations to Qingchuan Ma on completing her undergraduate studies at SJTU. We wish her continued growth and achievement in her future endeavors.
We are glad to welcome post-doc Kande Lin to our lab.
